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Santa Cruz Biotechnology ck7
Ck7, supplied by Santa Cruz Biotechnology, used in various techniques. Bioz Stars score: 96/100, based on 1811 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/ck7/Sox-2+Antibody/pm41877597-142-20-23
Average 96 stars, based on 1811 article reviews
ck7 - by Bioz Stars, 2026-10
96/100 stars

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Related Articles

Incubation:

Article Title: PrP C Glycoprotein Modulates Atmospherically Relevant Artificial Particulate Matter-Induced Development of Lung Cancer in Mice.
Article Snippet: .. The membranes were blocked with 5% skim milk (Bio- Rad) and then incubated with specific primary antibodies against Kras (TA801672-Origene), CK7 (ET1609-63-Huabio), Sox2 (sc365823-Santa Cruz Biotechnology), Ki67 (ab16667-Abcam), TTF1 (sc-53136-Santa Cruz Biotechnology), c-Myc (sc-42 Santa Cruz Biotechnology), PrPC (A03202- SPI bio), HIF-1α (NB-100-449Novus Biologicals), COX2 (BS1076-BioWord), IL-1β (sc-52012Santa Cruz Biotechnology), TNF-α (AB1793-Abcam), Sirt1 (Millipore, Billerica, MA),p-p53 (sc-71786 Santa Cruz Biotechnology), p53 (sc-55476 Santa Cruz Biotechnology), Caspase-1 (2225 Cell Signaling), and γH2AX (AB26350 Abcam). β-actin served as an internal control. .. Signals were visualized by a chemiluminescent detection kit (Amersham Pharmacia Biotech) and analyzed by a densitometric scanner (FUSION SOLO 4S.

Article Title: JPT2 in subclinical hypothyroidism-related miscarriage as a transcription co-factor: involvement of LEPR/STAT3 activation.
Article Snippet: Background and purpose Subclinical hypothyroidism (SCH) has been identified to be associated with implantation failure, in which the dysfunction of trophoblast cells is involved.. In this study, the transcriptomics of aborted placenta from SCH rats were analyzed.. Jupiter microtubule-associated homolog 2 (JPT2) was downregulated in the aborted placenta.

Control:

Article Title: PrP C Glycoprotein Modulates Atmospherically Relevant Artificial Particulate Matter-Induced Development of Lung Cancer in Mice.
Article Snippet: .. The membranes were blocked with 5% skim milk (Bio- Rad) and then incubated with specific primary antibodies against Kras (TA801672-Origene), CK7 (ET1609-63-Huabio), Sox2 (sc365823-Santa Cruz Biotechnology), Ki67 (ab16667-Abcam), TTF1 (sc-53136-Santa Cruz Biotechnology), c-Myc (sc-42 Santa Cruz Biotechnology), PrPC (A03202- SPI bio), HIF-1α (NB-100-449Novus Biologicals), COX2 (BS1076-BioWord), IL-1β (sc-52012Santa Cruz Biotechnology), TNF-α (AB1793-Abcam), Sirt1 (Millipore, Billerica, MA),p-p53 (sc-71786 Santa Cruz Biotechnology), p53 (sc-55476 Santa Cruz Biotechnology), Caspase-1 (2225 Cell Signaling), and γH2AX (AB26350 Abcam). β-actin served as an internal control. .. Signals were visualized by a chemiluminescent detection kit (Amersham Pharmacia Biotech) and analyzed by a densitometric scanner (FUSION SOLO 4S.

Immunohistochemistry:

Article Title: Clear cell renal cell carcinoma with cystic component similar to multilocular cystic renal neoplasm of low malignant potential: a rare pattern of cyst-dependent progression from multilocular cystic renal neoplasm of low malignant potential.
Article Snippet: .. The 4-μm-thick whole sections were performed IHC staining with an automated Ventana BenchMark XT system (Roche, Ventana Medical Systems Inc., Tucson) for the following antibodies: PAX8 (4H7B3, 1:100; ProteinTech Group, Rosemont, IL), CA-IX (ab1508, 1:1000; Abcam), CK7 (OV-TL12/30, prediluted; MXB Biotechnologies), Vimentin (V9, prediluted; MXB Biotechnologies), CD10 (56C6, prediluted; MXB Biotechnologies), P504s (13H4, prediluted; MXB Biotechnologies), TFE3 (SC-5958, 1:300; Santa Cruz, CA), 34βE12 (prediluted; MXB Biotechnologies). ..

Article Title: Clear cell renal cell carcinoma with cystic component similar to multilocular cystic renal neoplasm of low malignant potential: a rare pattern of cyst-dependent progression from multilocular cystic renal neoplasm of low malignant potential
Article Snippet: .. The 4-μm-thick whole sections were performed IHC staining with an automated Ventana BenchMark XT system (Roche, Ventana Medical Systems Inc., Tucson) for the following antibodies: PAX8 (4H7B3, 1:100; ProteinTech Group, Rosemont, IL), CA-IX (ab1508, 1:1000; Abcam), CK7 (OV-TL12/30, prediluted; MXB Biotechnologies), Vimentin (V9, prediluted; MXB Biotechnologies), CD10 (56C6, prediluted; MXB Biotechnologies), P504s (13H4, prediluted; MXB Biotechnologies), TFE3 (SC-5958, 1:300; Santa Cruz, CA), 34βE12 (prediluted; MXB Biotechnologies). ..

Staining:

Article Title: Clear cell renal cell carcinoma with cystic component similar to multilocular cystic renal neoplasm of low malignant potential: a rare pattern of cyst-dependent progression from multilocular cystic renal neoplasm of low malignant potential.
Article Snippet: .. The 4-μm-thick whole sections were performed IHC staining with an automated Ventana BenchMark XT system (Roche, Ventana Medical Systems Inc., Tucson) for the following antibodies: PAX8 (4H7B3, 1:100; ProteinTech Group, Rosemont, IL), CA-IX (ab1508, 1:1000; Abcam), CK7 (OV-TL12/30, prediluted; MXB Biotechnologies), Vimentin (V9, prediluted; MXB Biotechnologies), CD10 (56C6, prediluted; MXB Biotechnologies), P504s (13H4, prediluted; MXB Biotechnologies), TFE3 (SC-5958, 1:300; Santa Cruz, CA), 34βE12 (prediluted; MXB Biotechnologies). ..

Article Title: Clear cell renal cell carcinoma with cystic component similar to multilocular cystic renal neoplasm of low malignant potential: a rare pattern of cyst-dependent progression from multilocular cystic renal neoplasm of low malignant potential
Article Snippet: .. The 4-μm-thick whole sections were performed IHC staining with an automated Ventana BenchMark XT system (Roche, Ventana Medical Systems Inc., Tucson) for the following antibodies: PAX8 (4H7B3, 1:100; ProteinTech Group, Rosemont, IL), CA-IX (ab1508, 1:1000; Abcam), CK7 (OV-TL12/30, prediluted; MXB Biotechnologies), Vimentin (V9, prediluted; MXB Biotechnologies), CD10 (56C6, prediluted; MXB Biotechnologies), P504s (13H4, prediluted; MXB Biotechnologies), TFE3 (SC-5958, 1:300; Santa Cruz, CA), 34βE12 (prediluted; MXB Biotechnologies). ..

other:

Article Title: Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) deletion in myeloid cells augments cholestatic liver injury
Article Snippet: CK7 , Santa cruz biotechnology , SC-53263 , Mouse , IF , 1:100.

Immunofluorescence:

Article Title: Upregulation of SEMP1 Contributes to Improving the Biological Functions of Trophoblast via the PI3K/AKT Pathway in Preeclampsia.
Article Snippet: Disturbance of extravillous trophoblast infiltration is associated with preeclampsia (PE), a severe condition of pregnancy characterized by hypertension and proteinuria.. Senescence-associated epithelial membrane protein 1 (SEMP1), an integral membrane protein, is a vital component of tight junction strands in epithelial or endothelial cells, with no clear function reported in PE.. Gene Expression Omnibus (GEO) datasets showed that SEMP1 expression was downregulated in the placental tissues of PE patients, which was confirmed by assessing SEMP1 levels in placental samples collected in our hospital.

Expressing:

Article Title: Upregulation of SEMP1 Contributes to Improving the Biological Functions of Trophoblast via the PI3K/AKT Pathway in Preeclampsia.
Article Snippet: Disturbance of extravillous trophoblast infiltration is associated with preeclampsia (PE), a severe condition of pregnancy characterized by hypertension and proteinuria.. Senescence-associated epithelial membrane protein 1 (SEMP1), an integral membrane protein, is a vital component of tight junction strands in epithelial or endothelial cells, with no clear function reported in PE.. Gene Expression Omnibus (GEO) datasets showed that SEMP1 expression was downregulated in the placental tissues of PE patients, which was confirmed by assessing SEMP1 levels in placental samples collected in our hospital.



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ck7  (OriGene)
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Histopathological and immunohistochemical features of atypical eosinophilic renal cell tumours. A1–A6: Renal oncocytoma. A1: The tumour is well-circumscribed from the surrounding tissue and unencapsulated. A2: The tumour exhibits solid and nested/sheet-like growth with intervening edematous stroma. A3: <t>CK7</t> demonstrates focal strong cytoplasmic positive. A4: CD117 shows diffuse weak cytoplasmic positive. A5: CK20 is negative. A6: Colloidal iron staining is negative. B1–B6: Eosinophilic chromophobe renal cell carcinoma. B1: The tumour is relatively well-circumscribed, without involvement of the renal sinus fat. B2: Solidly packed tumour cells include distinct populations with botryoid morphology and eosinophilic cytoplasm. B3: CK7 shows diffuse strong cytoplasmic positive. B4: CD117 shows diffuse strong cytoplasmic positive. B5: CK20 is negative. B6: Colloidal iron staining is positive. C1–C6: Low-grade oncocytic tumour. C1: The tumour is well-circumscribed and unencapsulated. C2: Solid and acinar growth patterns are observed. C3: CK7 shows diffuse strong cytoplasmic positive. C4: CD117 is negative. C5: CK20 is negative. C6: Colloidal iron staining is negative. D1–D6: Eosinophilic vacuolated tumour. D1: The tumour is relatively well-circumscribed from the adjacent normal tissue, with scattered proliferative blood vessels within the tumour. D2: The tumour is arranged in solid nests and cords. D3: CK7 shows focal weak cytoplasmic positive. D4: CD117 shows diffuse moderate cytoplasmic positive. D5: CK20 is negative. D6: Colloidal iron staining is negative. E1–E6: Eosinophilic solid and cystic renal cell carcinoma. E1: The tumour is well-circumscribed, unencapsulated, and exhibits a cystic and solid structure. E2: The tumour shows cystic and solid growth patterns. E3: CK7 is negative. E4: CD117 is negative. E5: CK20 shows focal strong cytoplasmic positive. E6: Colloidal iron staining is negative. F1–F6: Normal renal tissue (Control). F1: Normal renal tissue, showing renal tubules, glomeruli, and thick-walled vessels. F2: Normal renal parenchyma. F3: CK7 shows diffuse strong cytoplasmic positive. F4: CD117 shows diffuse strong cytoplasmic positive. D5: CK20 is negative. F6: Colloidal iron staining is negative. Hematoxylin and eosin (H&E) staining x20 (A1-F1) and x40 (A2-F2). EnVision for CK7, CD117 and CK20 × 200. Colloidal iron staining x200
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Image Search Results


Histopathological and immunohistochemical features of atypical eosinophilic renal cell tumours. A1–A6: Renal oncocytoma. A1: The tumour is well-circumscribed from the surrounding tissue and unencapsulated. A2: The tumour exhibits solid and nested/sheet-like growth with intervening edematous stroma. A3: CK7 demonstrates focal strong cytoplasmic positive. A4: CD117 shows diffuse weak cytoplasmic positive. A5: CK20 is negative. A6: Colloidal iron staining is negative. B1–B6: Eosinophilic chromophobe renal cell carcinoma. B1: The tumour is relatively well-circumscribed, without involvement of the renal sinus fat. B2: Solidly packed tumour cells include distinct populations with botryoid morphology and eosinophilic cytoplasm. B3: CK7 shows diffuse strong cytoplasmic positive. B4: CD117 shows diffuse strong cytoplasmic positive. B5: CK20 is negative. B6: Colloidal iron staining is positive. C1–C6: Low-grade oncocytic tumour. C1: The tumour is well-circumscribed and unencapsulated. C2: Solid and acinar growth patterns are observed. C3: CK7 shows diffuse strong cytoplasmic positive. C4: CD117 is negative. C5: CK20 is negative. C6: Colloidal iron staining is negative. D1–D6: Eosinophilic vacuolated tumour. D1: The tumour is relatively well-circumscribed from the adjacent normal tissue, with scattered proliferative blood vessels within the tumour. D2: The tumour is arranged in solid nests and cords. D3: CK7 shows focal weak cytoplasmic positive. D4: CD117 shows diffuse moderate cytoplasmic positive. D5: CK20 is negative. D6: Colloidal iron staining is negative. E1–E6: Eosinophilic solid and cystic renal cell carcinoma. E1: The tumour is well-circumscribed, unencapsulated, and exhibits a cystic and solid structure. E2: The tumour shows cystic and solid growth patterns. E3: CK7 is negative. E4: CD117 is negative. E5: CK20 shows focal strong cytoplasmic positive. E6: Colloidal iron staining is negative. F1–F6: Normal renal tissue (Control). F1: Normal renal tissue, showing renal tubules, glomeruli, and thick-walled vessels. F2: Normal renal parenchyma. F3: CK7 shows diffuse strong cytoplasmic positive. F4: CD117 shows diffuse strong cytoplasmic positive. D5: CK20 is negative. F6: Colloidal iron staining is negative. Hematoxylin and eosin (H&E) staining x20 (A1-F1) and x40 (A2-F2). EnVision for CK7, CD117 and CK20 × 200. Colloidal iron staining x200

Journal: BMC Cancer

Article Title: Subtyping atypical eosinophilic renal cell tumours through integrated morphological, immunohistochemical, and mutational characters

doi: 10.1186/s12885-026-15870-1

Figure Lengend Snippet: Histopathological and immunohistochemical features of atypical eosinophilic renal cell tumours. A1–A6: Renal oncocytoma. A1: The tumour is well-circumscribed from the surrounding tissue and unencapsulated. A2: The tumour exhibits solid and nested/sheet-like growth with intervening edematous stroma. A3: CK7 demonstrates focal strong cytoplasmic positive. A4: CD117 shows diffuse weak cytoplasmic positive. A5: CK20 is negative. A6: Colloidal iron staining is negative. B1–B6: Eosinophilic chromophobe renal cell carcinoma. B1: The tumour is relatively well-circumscribed, without involvement of the renal sinus fat. B2: Solidly packed tumour cells include distinct populations with botryoid morphology and eosinophilic cytoplasm. B3: CK7 shows diffuse strong cytoplasmic positive. B4: CD117 shows diffuse strong cytoplasmic positive. B5: CK20 is negative. B6: Colloidal iron staining is positive. C1–C6: Low-grade oncocytic tumour. C1: The tumour is well-circumscribed and unencapsulated. C2: Solid and acinar growth patterns are observed. C3: CK7 shows diffuse strong cytoplasmic positive. C4: CD117 is negative. C5: CK20 is negative. C6: Colloidal iron staining is negative. D1–D6: Eosinophilic vacuolated tumour. D1: The tumour is relatively well-circumscribed from the adjacent normal tissue, with scattered proliferative blood vessels within the tumour. D2: The tumour is arranged in solid nests and cords. D3: CK7 shows focal weak cytoplasmic positive. D4: CD117 shows diffuse moderate cytoplasmic positive. D5: CK20 is negative. D6: Colloidal iron staining is negative. E1–E6: Eosinophilic solid and cystic renal cell carcinoma. E1: The tumour is well-circumscribed, unencapsulated, and exhibits a cystic and solid structure. E2: The tumour shows cystic and solid growth patterns. E3: CK7 is negative. E4: CD117 is negative. E5: CK20 shows focal strong cytoplasmic positive. E6: Colloidal iron staining is negative. F1–F6: Normal renal tissue (Control). F1: Normal renal tissue, showing renal tubules, glomeruli, and thick-walled vessels. F2: Normal renal parenchyma. F3: CK7 shows diffuse strong cytoplasmic positive. F4: CD117 shows diffuse strong cytoplasmic positive. D5: CK20 is negative. F6: Colloidal iron staining is negative. Hematoxylin and eosin (H&E) staining x20 (A1-F1) and x40 (A2-F2). EnVision for CK7, CD117 and CK20 × 200. Colloidal iron staining x200

Article Snippet: The antibodies used in the study are CK7 (EP16, Origene, Wuxi, China), CK20 (EP23, Origene, Wuxi, China), CD117 (EP10, Origene, Wuxi, China), mTOR (ab109268, Abcam, Shanghai, China), Vimentin (UMAB159, Origene, Wuxi, China), CAIX(H-11, Origene, Wuxi, China), SDHB (OTI1H6, Origene, Wuxi, China), FH (OTI1F10, Origene, Wuxi, China), Cathepsin K (ab37259, Abcam, Shanghai, China) and Pax8 (OTI6H8, Origene, Wuxi, China).

Techniques: Immunohistochemical staining, Staining, Control